SARS-CoV-2 Nucleocapsid Protein (NP)

SKU: 41A220

 

 

★ Download Datasheet PDF ★

 

 

 

Origin:   

Recombinant          

Cat No.:    

41A220

Source:

E.coli

Size:

0.1 mg

Tag:

No Tag

Purity:

>95%

 

Antigenicity Test

Antigenicity validated in 16 patient serum samples via ELISA by coating SARS-CoV-2 NP as capture antigen, with a detection rate of 93.75%.

Strong antiginetic response even in 70000-fold diluted patient serum.

 

 

Amino Acid Sequence

SDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTAAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSSADSTQA

 

  • INTRODUCTION

    Since December 2019, outbreak of SARS-CoV-2 infection has become a major epidemic threat in China and brought back the attention of pathogenic coronavirus to the spotlight. Nucleocapsid protein (NP) is the most abundant protein on the helical nucleocapsid of coronaviruses, which envelopes the entire genomic RNA. NP also interacts with other viron structural proteins to play important roles during host cell entry and virus particle assembly and release.

    Expressed in E.coli with total 418 AA. Mw: 45.5 KDa (calculated).

    Recombinant antigen for research use or manufacturing only.

  • AMINO ACID SEQUENCE

    SDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTAAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSSADSTQA

  • Antigenicity Test

    Antigenicity validated in 16 patient serum samples via ELISA by coating COVID-19 NP as capture antigen, with a detection rate of 93.75%.

    Strong antiginetic response even in 70000-fold diluted patient serum.

  • QUALITY CONTROL TEST

    BCA to determine quantity of the protein.

    SDS PAGE to determine purity of the protein.

  • FORMULATION

    As liquid with vials containing NP to 1.0mg/mL in 50mM Tris, 300mM NaCl, 10% Glycerol, PH8.0.

  • SDS-PAGE Gel

    See image

  • IMMUNOLOGICAL FUNCTION

    As an autoantigen, NP binds with IgG-type human auto-antibodies.

©2019 by ImmunoDiagnostics Limited.