SARS-CoV-2 Spike Protein S1 Receptor-Binding Domain (S1RBD)

SKU: 41A221

 

 

★ Download Datasheet PDF ★

 

 

 

Origin:    

Recombinant       

Cat No.:    

41A221

Source:

E.coli

Size:

0.1 mg

Tag:

No Tag

Purity:

>95%

 

Antigenicity Test

 

Antigenicity validated in patient serum samples via ELISA test by coating SARS-CoV-2 S1RBD as capture antigen.

Antiginetic response even in 900-fold diluted patient serum.

 

Amino Acid Sequence

NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATV

  • INTRODUCTION

    Since December 2019, outbreak of SARS-CoV-2 infection has become a major epidemic threat in China and brought back the attention of pathogenic coronavirus to the spotlight. Spike protein is an envelope-anchored protein that mediates the recognition and binding of SARS-CoV-2 to host cells. S1 can be further cleaved by the host protease into two subunits called S1 and S2, wherein the S1 polypeptide contain a receptor binding domain (RBD) crucial for the specific recognition and interaction with human receptor ACE2, which is the first and the most essential step for the virus infection.

    Expressed in E.coli with total 194 AA. Mw: 21.8 KDa (calculated).

    Recombinant antigen for research use or manufacturing only.

  • AMINO ACID SEQUENCE

    NITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATV

  • Antigenicity Test

    Antigenicity validated in patient serum samples via ELISA test by coating COVID-19 S1RBD as capture antigen.

    Antiginetic response even in 900-fold diluted patient serum.

  • QUALITY CONTROL TEST

    BCA to determine quantity of the protein.

    SDS PAGE to determine purity of the protein.

  • FORMULATION

    As liquid with vials containing S1RBD to 1.8 mg/mL in 50mM Tris, 300mM NaCl, 10% Glycerol, PH8.0.

  • SDS-PAGE Gel

    See image

©2019 by ImmunoDiagnostics Limited.