Anti-mouse FGF-21 Antibody, Rabbit pAb
FGF21 is a metabolic hormone mainly produced in liver. It regulates glucose and lipid metabolism through pleiotropic actions in multiple tissues, and protects against metabolic damages under various stresses.
In humans, high circulating FGF21 levels are found in obesity and multiple cardiometabolic disorders, including metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease and coronary artery disease. Serum FGF21 is a potential biomarker for the early detection and risk prediction of these diseases.
Recombinant full-length mouse FGF-21 expressed in E.Coli.
The antibody detects circular mouse FGF-21.
Solution in PBS, azide free.
Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
ELISA - This antibody can be used at 2 µg/ml with the appropriate secondary reagents to detect mouse FGF-21.
Western blot - This antibody can be used at 0.2 µg/ml to 0.5 µg/ml with the appropriate secondary reagents to detect mouse FGF-21.
Rabbit specific IgG was purified by mouse FGF-21 affinity chromatography.
Publications Citing IMD FGF-21(mouse), rabbit PAb
Liu Y, Palanivel R, Rai E, et al. Diabetes. 2015; 64(1): 36-48.
Li H, Gao Z, Zhang J, et al. Diabetes. 2012; 61(4): 797-806.