Polyclonal Antibody against Mouse FGF-21

Polyclonal Antibody against Mouse FGF-21

SKU: 12180

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FGF-21 (mouse), rabbit polyclonal antibody

Application  :  ELISA

Size              :  0.1 mg

  • INTRODUCTION

     

    FGF21 is a metabolic hormone mainly produced in liver. It regulates glucose and lipid metabolism through pleiotropic actions in multiple tissues, and protects against metabolic damages under various stresses.
    In humans, high circulating FGF21 levels are found in obesity and multiple cardiometabolic disorders, including metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease and coronary artery disease. Serum FGF21 is a potential biomarker for the early detection and risk prediction of these diseases.

  • DATA SHEET

  • IMMUNOGEN

    Recombinant full-length mouse FGF-21 expressed in E.Coli.

  • SPECIFICITY

    The antibody detects circular mouse FGF-21.

  • FORMULATION

    Solution in PBS, azide free.

  • STORAGE

    Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

  • APPLICATION/ USAGE

    ELISA - This antibody can be used at 2 µg/ml with the appropriate secondary reagents to detect mouse FGF-21.

    Western blot - This antibody can be used at 0.2 µg/ml to 0.5 µg/ml with the appropriate secondary reagents to detect mouse FGF-21.

  • PREPARATION

    Rabbit specific IgG was purified by mouse FGF-21 affinity chromatography.

     

     

  • Publications Citing IMD FGF-21(mouse), rabbit PAb

    Liu Y, Palanivel R, Rai E, et al. Diabetes. 2015; 64(1): 36-48.
     Li H, Gao Z, Zhang J, et al. Diabetes. 2012; 61(4): 797-806.
     

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