Human FGF-19 Elisa kit
Assay range : 15.6-2000pg/ml
The following standard curve is provided for demonstration only. A standard curve should be generated for each set of sample assay.
Fibroblast growth factor 19 (FGF-19) is a member of a subfamily of FGFs that includes FGF-21 and FGF-23, each member functions as an important regular of nutrient metabolism. The primary source of endocrine FGF-19 is the ileum, bile acids release into the intestine after a meal to induce expression of FGF-19. Circulating FGF-19 plays an important role in maintaining proper bile acid homeostasis. Several pharmacologic studies in hyperglycaemic, obese animal models have shown that FGF-19 can improve metabolic rate and lower serum glucose and hepatic triglyceride and cholesterol levels. Like insulin, FGF-19 functions as postprandial hormone to govern hepatic protein synthesis, glycogen synthesis and gluconeogenesis, but does not stimulate lipogenesis.
The lowest level of FGF-19 that can be measured by this assay is 15.6 pg/ml.
The antibodies used in this assay are specific to human FGF-19 and do not cross-react with human Adiponectin, FGF-21, FABP4, LCN2, RBP4 and PAI-1.
Intra-assay Precision (Precision within an assay) C.V< 4.5%.
Inter-assay Precision (Precision between assays) C.V< 5.6%.
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