Anti-human FGF-19 Antibody, Rabbit pAb
Polyclonal Antibody against Human FGF-19
Size: 0.1 mg
Fibroblast growth factor 19 (FGF-19) is a member of a subfamily of FGFs that includes FGF-21 and FGF-23, each member functions as an important regulator of nutrient metabolism . The primary source of endocrine FGF-19 is the ileum, bile acids release into the intestine after a meal to induce expression of FGF-19 . Circulating FGF-19 plays an important role in maintaining proper bile acid homeostasis . Several pharmacologic studies in hyperglycemic, obese animal models have shown that FGF-19 can improve metabolic rate and lower serum glucose and hepatic triglyceride and cholesterol levels [4,5]. Like insulin, FGF-19 functions as postprandial hormone to govern hepatic protein synthesis, glycogen synthesis and gluconeogenesis, but does not stimulate lipogenesis .
Recombinant full-length human FGF-19 expressed in E.coli.
The antibody detects circular human FGF-19.
Liquid in phosphate-buffered saline (PBS).
Store at –20°C for less than one week. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
ELISA - the antibody can be used as capture and detection antibody in ELISA.
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