©2019 by ImmunoDiagnostics Limited.

Human PAI-1 immunoassay kit

SKU: 31070

Human plasminogen activator inhibitor type-1 ELISA kit

Assay range :   0.016-2 ng/ml

Size :                96T/Kit

 

The following standard curve is provided for demonstration only. A standard curve should be generated for each set of sample assay.

  • INTRODUCTION

    Plasminogen activator inhibitor-1 (PAI-1) is the primary inhibitor of tissue-type and urokinase-type plasminogen activator, playing a major role in fibrinolysis1-2 . PAI-1 is mainly produced by the endothelium, but is also secreted by other tissue types, such as adipose tissue3 . It is normally present at low levels in plasma and tissue, but its expression and release increased in various disease states (such as a number of forms of cancer), as well as in obesity and the metabolic syndrome4 . PAI-1 is also involved in the pathophysiology of renal, pulmonary, cardiovascular, and metabolic diseases 5-8 . Elevated local or systemic PAI-1 can also exacerbate such pathologic conditions.

  • ASSAY CHARACTERISTICS

    A. Sensitivity:

    The lowest level of PAI-1 that can be measured by this assay is 0.031 ng/ml.

     

    B. Specificity:

    The antibodies used in this assay are specific to human PAI-1 and do not cross-react with mouse and rat PAI-1, and other cytokine or hormone molecules including human resistin, TNFα, ANGPTL4, insulin, leptin and IL6.

    C. Precision:

    Intra-assay Precision (Precision within an assay)

    Two samples of known concentration were tested 16 times on one plate

     

     

    Inter-assay Precision (Precision between assays)

    Four samples of known concentration were tested in 8 separate assays.

    D. Recovery:

    Serum samples were spiked with different amounts of human PAI-1 and assayed.

  • Publications Citing Human Adiponectin ELISa kit:

     

  • DATA SHEET

$440.00Price