©2019 by ImmunoDiagnostics Limited.

Human Rentinol Binding Protein 4(RBP4) ELISA kit

SKU: 31060

Assay range :   1.56-200 ng/ml

Size :                96T/Kit

 

The following standard curve is provided for demonstration only. A standard curve should be generated for each set of sample assay.

  • INTRODUCTION

    Retinol binding protein 4(RBP4), originally known as a specific transport of retinol in blood, is also a novel inflammatory and insulin resistance marker. Serum RBP4 levels are elevated in insulin-resistant mice and humans with obesity and type 2 diabetes. Animal experiments found that increased secretion of RBP4 might reduces insulin-dependent glucose uptake by muscle tissue by reducing the activity of PI(3)K (phosphoinositide 3-kinase), and increased hepatic glucose output by increasing the expression of the enzyme PEPCK2 . Studies suggested that elevated serum RBP4 was associated with components of the metabolic syndrome, including increased body-mass index, waist-to-hip ratio, serum triglyceride levels, and systolic blood pressure and decreased highdensity lipoprotein cholesterol levels4 . Furthermore, circulating RBP4 concentrations were associated with subclinical cardiovascular disease, which imply that RBP4 could be involved in the development of atherosclerosis5 .

  • ASSAY CHARACTERISTICS

    A. Sensitivity:

    The lowest level of RBP4 that can be detected by this assay is 1.56 ng/ml.

    B. Specificity:

    The antibody pair used in this assay is specific to human RBP4 and does not cross-react with mouse and rat RBP4, and other cytokine or hormone molecules.

    C. Precision:

    Intra-assay Precision (Precision within an assay)

    Three samples of known concentration were tested 16 times on one plate.

     

     

    Inter-assay Precision (Precision between assays)

    Three samples of known concentration were tested in 10 separate assays.

    D. Recovery:

    Serum samples were spiked with different amounts of human RBP4 and assayed.

  • Publications Citing Human Adiponectin ELISa kit:

     

  • DATA SHEET

$330.00Price