Humanized Monoclonal Antibody against SARS-CoV-2 S1RBD
Cat. No.: 41A244 Size: 10 or 100µg
Type: Genetically engineered recombinant monoclonal IgG antibody
The SARS-CoV-2 glycosylated spike (S) protein highly exposed on the viral surface is a major determinant for virus binding and invasion into hose cells, which is a main target for neutralization antibody. The receptor-binding domain (RBD) in SARS-CoV-2 S protein is responsible for binding to human and bat angiotensin-converting enzyme 2 (ACE2) receptors.
The cDNA encoding the highly variable region of the antibody recognizing S1RBD from mammalian cells were identified by phage display library, fused with the Fc fragment of human IgG1, and expressed in Chinese Hamster Ovary (CHO) cells.
FORMULATION AND STORAGE
Liquid in PBS with 0.02% azide, PH7.4. Store at -80°C. Recommend to aliquot the protein into smaller quantities. Avoid repeated freeze-thaw cycles.
ELISA and other applications. Optimal concentration/dilution should be determined by the end user.