Major urinary protein 1 (MUP-1), also known as Mup7, Up-1, Ltn-1, Mup-1, Mup-a, Mup10 and Lvtn-1, is a low molecular weight secreted protein produced predominantly from the liver [1]. Structurally it belongs to the lipocalin family, which carries small hydrophobic ligands such as pheromones. MUP-1 is an important player in regulating energy expenditure and metabolism in mice, and its deficiency might contribute to the metabolic dysregulation in obese/diabetic mice [2].

Recombinant full-length mouse MUP-1 expressed in E.coli.

The antibody detects circular/urinary mouse MUP-1.

Liquid in phosphate-buffered saline (PBS).

Store at –20°C for less than one week. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

ELISA - This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect mouse MUP-1.

Western blot

Antigen affinity-purified

1. McIntosh, I., and Bishop, J. O. (1989) Mol. Cell. Biol. 9, 2202–2207.

2. Zhou Y, Jiang L, Rui L. (2009) J Biol Chem. 284(17):11152-9.