Anti-human Adiponectin Antibody, Rabbit pAb
Adiponectin, also termed gelatin-binding protein-28 (GBP28), AdipoQ, ACP30 (Acrp30), or apM, is a major adipocyte-secreted adipokine which abundantly present in the circulation as three distinct oligomeric complexes: LMW(67kDa), MMW(167kDa) and HMW(300kDa) adiponectin. Its levels are decreased in insulin resistant, diabetes and cardiovascular disease. Conversely, elevation of circulating adiponectin concentrations can alleviate various vascular dysfunctions in animal models, suggesting this adipokine exerts vasculoprotective effects. In addition, adiponectin may also be of importance in the development and progression of several malignancies.
Rabbit crude IgG was purified by protein-G column
Recombinant full-length human adiponectin expressed in mammalian cells
The antibody detects three types of circular human adiponectin and monomer (30kDa) adiponectin
Solution in PBS.
Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
Western blot - This antibody can be used at 0.1 - 0.2 µg/mL with the appropriate secondary reagents to detect human adiponectin.
ELISA - This antibody can be used at 0.5 - 1.0 µg/mL with the appropriate secondary reagents to detect human Adiponectin.