Anti-human Autotaxin Antibody, Rabbit pAb

Anti-human Autotaxin Antibody, Rabbit pAb

SKU: 11770

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Polyclonal Antibody against Human Autotaxin

Size: 100 ug

Host: Rabbit

  • INTRODUCTION

    Autotaxin (ATX, ENPP2) is a secreted glycoprotein with phosphodiesterase (PDE) activity. It is one of the member in the nucleotide pyrophosphatase/ phosphodiesterase family (NPPs) family. ATX has lysophospholipase D activity that converts lysophosphatidylcholine into LPA, and it was originally identified as a tumor cell-motility-stimulating factor. LPA, which specifically binds to G protein-coupled receptors (GPCR), plays a wide range of biological activities, including cell hyperproliferation, which may contribute to oncogenesis and metastasis. 

    ATX has been to be overexpressed in many tumor cells, and thus plays an important role in tumor development and metastasis. In addition, ATX also plays an important role in nervous and immune systems.

     

  • IMMUNOGEN

    Recombinant human autotaxin in mammalian cells. (Cat. No.: 41770)

  • ISOTYPE/ PREPARATION

    Rabbit specific IgG was purified by antigen affinity chromatography

  • STORAGE

    Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

  • PURIFICATION METHOD

    Affinity chromatography on a column with immobilized antigen.

     

     

  • SPECIES REACTIVITY

    Mouse. Not yet tested in other species

  • FORMULATION

    Solution in PBS.

  • APPLICATION

    Western blot: This antibody can be used as primary antibody in western blot assay to detect human autotaxin.

    ELISA - This antibody can be used as capture antibody in Human autotaxin Elisa (Cat. No.: 31770).

  • SPACIFICITY

    The antibody detects human autotaxin.

$200.00Price

For bulk order (QTY: 5 or more), please contact us for quote

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