Anti-Autotaxin, Rabbit pAb (Human)

SKU: 11770

Size: 100 ug                         Host: Rabbit

  • INTRODUCTION

    Autotaxin (ATX, ENPP2) is a secreted glycoprotein with phosphodiesterase (PDE) activity. It is one of the member in the nucleotide pyrophosphatase/ phosphodiesterase family (NPPs) family. ATX has lysophospholipase D activity that converts lysophosphatidylcholine into LPA, and it was originally identified as a tumor cell-motility-stimulating factor. LPA, which specifically binds to G protein-coupled receptors (GPCR), plays a wide range of biological activities, including cell hyperproliferation, which may contribute to oncogenesis and metastasis. 

    ATX has been to be overexpressed in many tumor cells, and thus plays an important role in tumor development and metastasis. In addition, ATX also plays an important role in nervous and immune systems.

     

  • DATA SHEET

  • IMMUNOGEN

    Recombinant human autotaxin in mammalian cells. (Cat. No.: 41770)

  • ISOTYPE/ PREPARATION

    Rabbit specific IgG was purified by autotaxin affinity chromatography

  • STORAGE

    Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

  • PURIFICATION METHOD

    Affinity chromatography on a column with immobilized protein G.

     

     

  • SPECIES REACTIVITY

    Human. Not yet tested in other species

  • FORMULATION

    Solution in PBS.

  • APPLICATION

    Western blot: This antibody can be used as primary antibody in western blot assay to detect human autotaxin.

    ELISA - This antibody can be used as capture antibody in Human autotaxin Elisa (Cat. No.: 31770).

  • SPACIFICITY

    The antibody detects human autotaxin.

$200.00Price

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