Anti-human LCN2 Antibody, Mouse mAb, clone 2G1
Application : ELISA capture
Size : 0.1 mg
Recombinant human lipocalin-2
Human lipocalin-2, MAb, clone 2C3
Human lipocalin-2 Elisa Kit
Lipocalin-2(LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), 24p3, or neutrophil lipocalin (NL), is a 25-kDa secretory glycoprotein. 1 LCN2 has been implicated in a variety of cellular processes including the innate immune response, differentiation, tumorigenesis, and cell survival 2-3. It appears to be upregulated in various inflammation and infection conditions. Several reports suggest that LCN2 may represent a sensitive biomarker for various renal injuries4 and is associated with several types of cancers, including breast cancer,5 ovarian, colorectal, and pancreatic cancers. 6-7 Furthermore, a growing body of evidence suggests that serum levels of lipocalin-2 are correlated with obesity, insulin resistance, hyperglycemia, coronary heart disease and fatty liver disease in humans.8-11
Recombinant full-length human lipocalin-2 in E.coli. (Cat. No: 41050).
The antibody detects human LCN2.
ISOTYPE/ LIGHT CHAIN TYPE
Mouse IgG1/ Kappa
Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
Affinity chromatography on a column with immobilized protein G.
This antibody can be used as a capture antibody in a human Lipocalin-2 ELISA in combination with monoclonal anti-human Lipocalin-2 antibody clone 2C3 (Cat. No.: 21051)
Solution in PBS.
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 Yang, J. et al. (2002) Mol. Cell. 10:1045-56.
 Flo, T.H. et al. (2004) Nature 432:917-21.
 Mishra, J. et al. (2005) Lancet 365:1231-6.
 Yang, J. et al. (2009) Proc Natl Acad Sci U S A 106(10):3913-8.
 Hanai, J. et al. (2005) J. Biol. Chem. 280:13641-7.
 Lee, H.J. et al. (2005) Int. J. Cancer 118:2490-7.
 Wang Y, et al. (2007) Clin Chem 53(1):34-41.
 Yan QW, et al. (2007) Diabetes 56(10):2533-40.
 Ruby LC Hoo, et al. (2008) Expert Rev. Endocrinol Metal 3(1):29-41.  Milner KL, et al. Hepatology [Epub ahead of print]