Anti-mouse LCN2 Antibody, Rabbit pAb

Anti-mouse LCN2 Antibody, Rabbit pAb

SKU: 12050

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Polyclonal Antibody against Mouse LCN2

Application: ELISA, WB, IP

Size: 0.1 mg

Host: Rabbit

  • INTRODUCTION

    Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), 24p3, siderocalin, or neutrophil lipocalin (NL), is a secretory glycoprotein expressed in liver, lung, kidney, adipocytes, activated neutrophils and macrophages.
    Lipocalin-2 is upregulated under various inflammation and infection conditions and can be served as a sensitive biomarker for various renal injuries. Serum levels of lipocalin-2 are positively correlated with obesity, insulin resistance, hyperglycemia, coronary heart disease and fatty liver disease in humans.

  • IMMUNOGEN

    Recombinant full-length mouse LCN2 expressed in E.Coli.

  • SPECIFICITY

    The antibody detects circular mouse LCN2.

  • FORMULATION

    Solution in PBS.

  • STORAGE

    Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

  • APPLICATION/ USAGE

    ELISA, Western blot and immunostaining.

  • PURIFICATION METHOD

    The antibody is purified by antigen affinity chromatography.

  • PUBLICATIONS CITING THIS PRODUCT

    1. Ye D, Yang K, Zang S, Lin Z, Chau HT, Wang Y, Zhang J, Shi J, Xu A, Lin S, Wang Y. Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2. Journal of hepatology. 2016 Nov 1;65(5):988-97.
    2. Ye D, Yang K, Zang S, Lin Z, Chau HT, Wang Y, Zhang J, Shi J, Xu A, Lin S, Wang Y. Corrigendum to “Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2”. Journal of hepatology. 2017 Mar 1;66(3):669.
    3. Sun WY, Bai B, Luo C, Yang K, Li D, Wu D, Félétou M, Villeneuve N, Zhou Y, Yang J, Xu A. Lipocalin-2 derived from adipose tissue mediates aldosterone-induced renal injury. JCI insight. 2018 Sep 6;3(17).
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