Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), 24p3, siderocalin, or neutrophil lipocalin (NL), is a secretory glycoprotein expressed in liver, lung, kidney, adipocytes, activated neutrophils and macrophages.
Lipocalin-2 is upregulated under various inflammation and infection conditions and can be served as a sensitive biomarker for various renal injuries. Serum levels of lipocalin-2 are positively correlated with obesity, insulin resistance, hyperglycemia, coronary heart disease and fatty liver disease in humans.
ImmunoDiagnostics team is the first to report lipocalin 2 as a biomarker for metabolic inflammation and insulin resistance, and has developed a series of related products:
Bioactive proteins and antibodies
Immunoturbidimetric (ITA) Assay