top of page
Anti-human LCN2 Antibody, Mouse mAb, clone 2C3

Anti-human LCN2 Antibody, Mouse mAb, clone 2C3

SKU: 21051

★ Download Datasheet PDF ★


Monoclonal Antibody against Human LCN2

Application: ELISA

Size: 0.1 mg

Host: Mouse


    Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), 24p3, or neutrophil lipocalin (NL), is a 25-kDa secretory glycoprotein [1]. LCN2 has been implicated in a variety of cellular processes including the innate immune response, differentiation, tumorigenesis, and cell survival [2-3]. It appears to be upregulated in various inflammation and infection conditions. Several reports suggest that LCN2 may represent a sensitive biomarker for various renal injuries [4] and is associated with several types of cancers, including breast cancer [5], ovarian, colorectal, and pancreatic cancers [6-7]. Furthermore, a growing body of evidence suggests that serum levels of LCN2 are correlated with obesity, insulin resistance, hyperglycemia, coronary heart disease and fatty liver disease in humans [8-11].


    Recombinant full-length human lipocalin-2 (Cat. No: 41050) in E.coli.


    The antibody detects human LCN2.


    Protein G affinity purification


    Liquid in phosphate-buffered saline (PBS).


    Store at –20°C for less than one week. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.


    This antibody can be used as a capture antibody in a human lipocalin-2 ELISA in combination with monoclonal anti-human lipocalin-2 antibody clone 2C3 (Cat. No.: 21050) as detection antibody.


    [1] Kjeldsen, L. et al. (1993) J. Biol. Chem. 268:10425-32

    [2] Yang, J. et al. (2002) Mol. Cell. 10:1045-56.

    [3] Flo, T.H. et al. (2004) Nature 432:917-21.

    [4] Mishra, J. et al. (2005) Lancet 365:1231-6.

    [5] Yang, J. et al. (2009) Proc Natl Acad Sci U S A 106(10):3913-8.

    [6] Hanai, J. et al. (2005) J. Biol. Chem. 280:13641-7.

    [7] Lee, H.J. et al. (2005) Int. J. Cancer 118:2490-7.

    [8] Wang Y, et al. (2007) Clin Chem 53(1):34-41.

    [9] Yan QW, et al. (2007) Diabetes 56(10):2533-40.

    [10] Ruby LC Hoo, et al. (2008) Expert Rev. Endocrinol Metal 3(1):29-41.

    [11] Milner KL, et al. Hepatology [Epub ahead of print].


The currency used on this website is United States Dollars (USD). All prices are displayed and transactions are processed in USD. For orders outside Hong Kong or if you would like to have other currencies available, please contact us for a quote.

bottom of page