Plasminogen activator inhibitor type-1 protein (PAI-1)

Plasminogen activator inhibitor-1 (PAI-1) is the primary inhibitor of tissue-type and urokinase-type plasminogen activator, playing a major role in fibrinolysis.

PAI-1 is mainly produced by the endothelium, but is also secreted by other tissue types, such as adipose tissue. It is normally present at low levels in plasma and tissue, but its expression and release increased in various disease states (such as a different forms of cancer), as well as in obesity and the metabolic syndrome.

PAI-1 is also involved in the pathophysiology of renal, pulmonary, cardiovascular, and metabolic diseases. Elevated local or systemic PAI-1 can also exacerbate such pathologic conditions.

ImmunoDiagnostics has developed a series of PAI-1 related products, such as ELISA Kits and Antibodies.

ELISA Kits

Human PAI-1

PAI-1 (human), MAb, clone 3H3

PAI-1 (human), MAb, clone 3H3

$225.00Price
Human PAI-1, rabbit PAb

Human PAI-1, rabbit PAb

$200.00Price
Human PAI-1 immunoassay kit

Human PAI-1 immunoassay kit

$440.00Price

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