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ANA-17s (Ready-to-use ImmunoBlot Strips)

ANA-17s (Ready-to-use ImmunoBlot Strips)

SKU: 61001

★ Download Datasheet PDF ★

 

Size: 24 tests/box

 

Products

Indications

Cat. No.

ANA-19s

SLE, MCTD, SS, CREST, PM/DM, SSc

61000

ANA-17s

SLE, MCTD, SS, CREST, PM/DM, SSc

61001

ANA-12s-a

SLE, MCTD, SS

61002

ANA-12s-b

SLE, MCTD, PM/DM

61003

ANA-9s

SLE, MCTD

61004

ANA-6s

SLE

61005

  • INTRODUCTION

    Antinuclear antibodies (ANA) are a group of autoantibodies that specifically target substances in the nucleus of cells. One group of ANAs represent autoantibodies against extractable nuclear antigens, such as SS-A/Ro, SS-B/La, Sm, RNP, Scl-70 and Jo-1, which are mainly ribonucleoproteins and nuclear enzymes. Another group of ANAs are against nucleic acids (dsDNA), complexes of nuclear proteins and histones.

    Detection and classification of these ANAs in human blood are important for differential diagnosis of systemic autoimmune diseases (SAD). Utilization of high-quality autoantigens for the screening and semi-quantification of specific ANAs has been routinely used in clinical practice for precision diagnosis and monitoring the progression of these diseases.

  • ASSAY CHARACTERISTICS

    Autoantigens

    Clinical Indication

    dsDNA

    SLE (highly specific marker)

    Histones

    SLE; drug induced form of SLE; systemic sclerosis; rheumatoid arthritis

    SmB/B’ & SmD1 & SmD3

    SLE (highly specific marker)

    P0 & PCNA

    SLE

    snRNP A & C & 68/70 (snRNPs)

    MCTD (primarily isolated appearance);

    SLE; Sjogren’s syndrome; systemic sclerosis (combination with other antibodies)

    SSA/Ro52 & SSA/Ro60 & SSB/La

    Sjogren’s syndrome (primary, secondary);

    SLE (dermal forms LE); neonatal LE syndrome

    Jo-1

    DM/PM; increased risk of pulmonary fibrosis

    PL-7 & PL-12

    DM/PM; antisynthetase syndrome (myositis, interstitial pulmonary fibrosis, arthritis)

    PmScl-75

    DM/PM; systemic sclerosis

    CENP-A & CENP-B

    CREST syndrome; SSc (limited form without the appearance of antigen Scl-70)

    Scl-70

    SSc; overlap syndrome scleromyositis (highly specific marker)

  • DATA SHEET

  • UNIQUE ADVANTAGES

    • Ready-to-use components;
    • Simultaneous diagnosis of 7 major SADs in 1 test;
    • Easy interpretation;
    • Superior batch-to-batch reproducibility;
    • Excellent specificity and sensitivity (> 95%);
    • Rapid procedures (~ 35 minutes);
    • Positive and negative controls;
    • Strict quality control and clinical validation.
$363.00Price

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