PDGF-AA, Mouse, E.coli
Species: | Mouse |
Expression System: | E.coli |
MW: | 29 kDa (reducing) |
Accession: | P20033-1 |
Cat No.: | UA040104 |
Endotoxin: | ＜0.1 EU/μg |
Purity: | >95% as determined by SDS-PAGE |
INTRODUCTION
Platelet-derived growth factor (PDGF) is a family of three disulfide-linked glycoprotein dimers of M.W. 29kDa-32kDa that arise from stochastic assembly of the homologous subunits, A-chain and B-chain, yielding the heterodimer PDGF-AB and homodimers PDGF-AA and PDGF-BB. PDGF-AA and its receptor represent an important epithelial-mesenchymal interaction which plays a critical role in early lung branching morphogenesis.
Amino Acid Sequence
Ser87-Thr211
MSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATSNLNPDHREEETGRRRESGKNRKRKRLKPTPhysical Appearance:
Lyophilized powder
Buffer
PBS, pH7.4
Reconstitution
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
- 1 week, 2 to 8 °C under sterile conditions after reconstitution.
Note: Please avoid repeated freeze-thaw cycles