FABP4 (human), rabbit PAb
Fatty-acid binding protein 4 (human), rabbit polyclonal
Application : WB, IP
Size : 100 ug
INTRODUCTION
FABP-4, also termed adipocyte fatty-acid binding protein (A-FABP) or AP2, has been shown to play a key role in obesity and metabolic syndrome. A-FABP knockout mice are substantially protected from insulin resistance, dyslipidemia, type 2 diabetes and fatty liver disease, despite of increased adipocity.
In clinical studies, increased circulating A-FABP levels are found in obese subjects and associated with non-alcoholic fatty liver disease, stroke, and carotid atherosclerosis.DATA SHEET
IMMUNOGEN
Recombinant full-length human FABP4 expressed in E.coli.
SPECIFICITY
The antibody detects human FABP4
FORMULATION
Solution in PBS.
STORAGE
Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
APPLICATION/ USAGE
Western blot - This antibody can be used at 0.5 - 1 μg/mL with the appropriate secondary reagents to detect human FABP4.
Immunoprecipitation, ELISA and immunocytochemistry are not tested.
ISOTYPE/PREPARATION
Rabbit crude IgG was purified by protein-G column