P0 (Human Ribosomal Phosphoprotein P0)

P0 (Human Ribosomal Phosphoprotein P0)

SKU: 41560

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Origin:

Recombinant

Cat. No.:

41560

Tag:

N-terminal 6xHis

Size:

0.1 mg

Source:

E.coli

Purity:

>90%

Other names:

P0, RPLP0

Species:

Human

 
  • INTRODUCTION

    The ribosomal phosphoproteins (P protein antigens) are associated with the large ribosomal subunit and therefore are antigenic targets with a cytoplasmic localization. Three P proteins have been described: P0 with a molecular weight of 36 kDa, P1 (19 kDa) and P2 (17 kDa).

    Autoantibodies against ribosomal P proteins are present in 10 % of SLE patients.

  • IMMUNOLOGICAL FUNCTION

    As an autoantigen, P0 binds with IgG-type human auto-antibodies.

  • AMINO ACID SEQUENCE

    MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSENLYFQGAPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFVAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD

  • APPLICATIONS

    Standard ELISA test, line/dot assay and microarray assay with positive/negative sera panels.

  • FORMULATION

    Liquid in PBS(10mM Na2HPO4, 2mM KH2PO4, 2.7mM KCl,137mM NaCl, Protease inhibitor, pH7.4).

  • DESCRIPTION

    Expressed in E.coli with total 360 AA.

    Mw: 39.2 kDa (calculated).

    N-terminal 6xHis-tag, Xpress Epitope, EK recognition site and TEV cleavage site, 44 extra AA (highlighted).

    Recombinant antigen for research use or manufacturing only.

  • STORAGE

    Store at –80°C.  Avoid repeated freezing/thawing cycles.

  • QUALITY CONTROL TEST

    BCA to determine quantity of the protein.

    SDS PAGE to determine purity of the protein.

$199.00Price

For bulk order (QTY: 5 or more), please contact us for quote

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