Expressed in E.coli with total 323 AA. Mw: 35 KDa (calculated).
Recombinant antigen for research use or manufacturing only.

Arginase 1 (ARG1) is a binuclear manganese metalloenzyme. There are two isozymes of arginase in mice, ARG1 and ARG2. ARG1 is liver-specific and is the primary isozyme involved in the urea cycle. It catalyzes the hydrolysis of L-arginine to form L-ornithine and urea. This reaction is the final step in the urea cycle, which is crucial for the detoxification of ammonia in the body. It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer. Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia.

Lyophilized at 1 mg/mL in NaCl 300mM, KCl 2.7mM, Na2HPO4 10mM, KH2PO4 1.8mM, pH 7.4.

Cell culture, animal studies, ELISA and Western blotting.

BCA to determine quantity of the protein.
SDS PAGE to determine purity of the protein.

Store lyophilized protein at –20°C. Aliquot reconstituted protein and store at –80°C.
Avoid repeated freezing/thawing cycles.