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Polyclonal antibody against Human CDCP1

Polyclonal antibody against Human CDCP1

SKU: 11C011

★ Download Datasheet PDF ★

Size: 100 μg

Host: Human


    CDCP1, also known as SIMA135, is a novel 140 kDa type I transmembrane glycoprotein with three CUB protein-protein interaction domains in its 635 aa extracellular regions. The cytoplasmic region with 148 aa contains canonical phosphorylation sites for Src kinase family members and binding sites for SH3 domains. A secreted 310 aa residue variant of CDCP1 is also present by alternative splicing. It is also possible for the type I membrane CDCP1 to undergo proteolytic cleavage at its amino-terminal region, which is around 265 aa long. CDCP1 is present on the surface of epithelial and bone marrow-derived stem cells. The extracellular regions of mouse CDCP1 and human CDCP1 are 84% identical in terms of amino acids.

  • Purification

    Antigen affinity purification

  • Immunogen

    Recombinant human CDCP1 protein (Cat. No.: 41A323) expressed in mammalian cells.

  • Species reactivity

    The antibody detects human CDCP1 in western blot and Elisa.

  • Formulation & Storage

    Liquid in phosphate-buffered saline (PBS). Store at –20°C for less than one week. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

  • Application/Usage

    Western blot – This antibody can be used as a primary antibody in western blot to detect human CDCP1.
    ELISA - This antibody can be used as a capture antibody in human CDCP1 ELISA.


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