FGF21 is a metabolic hormone that is mainly produced in liver. It regulates glucose and lipid metabolism through pleiotropic actions in multiple tissues, and protects against metabolic damages under various stresses.
In humans, high circulating FGF21 levels are found in obesity and multiple cardiometabolic disorders, including metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease and coronary artery disease. Serum FGF21 is a potential biomarker for the early detection and risk prediction of these diseases.
ImmunoDiagnostics has developed a series of FGF-21 related products, such as ELISA Kits and Bioactive proteins, which have been used globally for over a decade.